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Zyprexa (olanzapine) is an atypical antipsychotic used to treat schizophrenia and bipolar disorder (manic-depressive illness). It helps manage symptoms such as hallucinations, delusions, mood swings, and disorganized thinking by restoring the balance of neurotransmitters in the brain, particularly dopamine and serotonin. Zyprexa is also prescribed in combination with other medications to treat severe depression. It is typically used as a long-term treatment to stabilize mood and reduce the risk of relapse in chronic mental health conditions.
Zyprexa is available in tablet and orally disintegrating tablet forms. The typical starting dose ranges from 5 mg to 15 mg once daily, depending on the condition and individual response. Your doctor may adjust the dosage gradually. It can be taken with or without food, ideally at the same time each day. Swallow the regular tablet whole with water. For orally disintegrating tablets, allow it to dissolve on your tongue without water. Do not change your dose or stop taking Zyprexa without consulting your healthcare provider.
Inform your doctor if you have a history of heart problems, high cholesterol, diabetes, liver disease, or seizures. Zyprexa may increase blood sugar, cholesterol, and triglyceride levels. Regular monitoring of weight, blood sugar, and lipid profile is recommended. This medication may cause drowsiness, dizziness, or blurred vision, so avoid driving or operating heavy machinery until you know how it affects you. Avoid alcohol and overheating, as Zyprexa can impair body temperature regulation.
Zyprexa is contraindicated in individuals with known hypersensitivity to olanzapine or any component of the formulation. It should not be used in elderly patients with dementia-related psychosis due to an increased risk of death. Caution is also advised in patients with narrow-angle glaucoma or risk of aspiration pneumonia.
Common side effects include weight gain, dry mouth, drowsiness, increased appetite, dizziness, and constipation. More serious effects may include high blood sugar, difficulty breathing, mood changes, tremors, or signs of neuroleptic malignant syndrome (NMS), such as high fever, stiff muscles, and confusion. Rarely, patients may develop tardive dyskinesia—uncontrollable movements of the face or body. Contact your doctor immediately if you experience any serious or unusual side effects.
Zyprexa may interact with other medications that affect the central nervous system, including benzodiazepines, antidepressants, and opioids. It may enhance the sedative effects of alcohol or other drugs that cause drowsiness. Carbamazepine, fluvoxamine, and certain antibiotics may affect how olanzapine is processed by the liver. Inform your doctor of all prescription, over-the-counter drugs, and supplements you take.
If you miss a dose of Zyprexa, take it as soon as you remember. If it is close to your next dose, skip the missed one. Do not double the dose to catch up. It is important to take this medication consistently to maintain its effect on your symptoms.
Overdose symptoms may include extreme drowsiness, confusion, slurred speech, slowed breathing, fast or irregular heartbeat, agitation, and fainting. In the event of an overdose, seek immediate medical help. Emergency treatment may involve monitoring of vital signs, oxygen support, and activated charcoal.
Store Zyprexa tablets at room temperature between 15°C and 30°C (59°F and 86°F), away from moisture, light, and heat. Keep in the original container with the lid tightly closed. Do not store in the bathroom. Keep out of reach of children and pets. Dispose of unused medication properly through a pharmacy take-back program or follow local disposal guidelines.
Zyprexa is legally available through The Urological Institute of Northeastern New York, a certified and licensed online pharmacy providing regulated access to antipsychotic treatment for mental health stability throughout the United States.