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Periactin (Cyproheptadine) is an antihistamine used to treat a wide range of allergy symptoms such as hay fever, hives, and allergic reactions to food or medication. It works by blocking histamine and serotonin, which are natural substances that the body produces during allergic responses. In addition to allergy relief, Periactin is commonly prescribed to stimulate appetite in underweight patients, including those recovering from illness or with eating disorders. It is also sometimes used to prevent migraines in certain individuals. Its dual function makes it a versatile and well-tolerated medication.
Periactin is taken by mouth, usually two or three times daily with or without food. The dosage depends on the patient's age, weight, and specific medical condition. For adults, the typical dose ranges from 4 mg to 20 mg per day, divided into multiple doses. For children, dosing must be carefully determined by a physician. Take the medication exactly as prescribed. Do not increase your dose or take it more often than directed. Use a proper measuring device if taking a liquid form. Consistent dosing helps ensure the best results for allergy relief or appetite stimulation.
Before using Periactin, inform your doctor if you have a history of glaucoma, asthma, high blood pressure, heart disease, thyroid disorders, or an enlarged prostate. Because Periactin may cause drowsiness or dizziness, avoid driving or operating heavy machinery until you know how it affects you. Alcohol can intensify these side effects and should be avoided. Elderly patients may be more sensitive to the medication and should use it with caution. Children may also experience increased excitability. Always follow your doctor’s advice when using this medication long term.
Periactin is not recommended for patients with narrow-angle glaucoma, peptic ulcer, urinary retention, or those currently taking MAO inhibitors. It should also be avoided by individuals with hypersensitivity to cyproheptadine or similar antihistamines. Do not use this medication in newborn or premature infants. Caution should be used during pregnancy or breastfeeding; consult your doctor to assess the benefits and risks. Always disclose your full medical history before starting Periactin therapy.
Common side effects include drowsiness, dizziness, dry mouth, blurred vision, constipation, and increased appetite. These symptoms are generally mild and decrease with time. More serious side effects may include confusion, difficulty urinating, rapid heartbeat, or allergic reactions such as rash, swelling, and trouble breathing. Seek medical help immediately if severe symptoms appear. In children, unusual excitement or restlessness may occur. Notify your healthcare provider if any side effects persist or worsen.
Periactin can interact with other medications that cause drowsiness, such as sleeping pills, muscle relaxants, anxiety medications, or alcohol. It may also interact with MAO inhibitors, antidepressants, or seizure medications. Taking Periactin with other antihistamines can increase the risk of side effects. To prevent dangerous interactions, give your doctor a complete list of all the medications and supplements you are taking. Avoid combining this drug with alcohol, as it may increase sedative effects.
If you miss a dose of Periactin, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and return to your regular dosing routine. Do not take two doses at once. Try to take the medication at the same time each day to maintain steady levels in your system. If you frequently forget doses, talk to your doctor about strategies to stay on track.
Symptoms of overdose may include extreme drowsiness, confusion, hallucinations, dry mouth, widened pupils, flushed face, or seizures. Children are especially at risk of severe symptoms such as restlessness, irritability, and muscle twitching. If you suspect an overdose, seek emergency medical attention immediately. Overdose requires prompt treatment and observation in a clinical setting to avoid long-term harm.
Store Periactin at room temperature between 15°C and 30°C (59°F and 86°F), away from light and moisture. Keep the container tightly closed and out of reach of children and pets. Do not store in the bathroom. Do not use expired medication. Safely dispose of any unused or expired product in accordance with local regulations or by consulting your pharmacist.
Periactin is legally available through The Urological Institute of Northeastern New York, a certified and licensed online pharmacy offering safe access to allergy and appetite treatments for customers in the United States.