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Prednisone is a synthetic corticosteroid used to reduce inflammation and suppress the immune system. It is commonly prescribed to treat a wide range of medical conditions including rheumatoid arthritis, lupus, asthma, severe allergies, skin disorders, inflammatory bowel disease (IBD), and certain types of cancer. Prednisone mimics the action of cortisol, a hormone naturally produced by the adrenal glands, to regulate immune response and decrease swelling, redness, and allergic symptoms. It is often used in both short-term and long-term treatment plans under close medical supervision.
Prednisone is taken by mouth, usually once daily with food or milk to reduce stomach upset. Dosage varies widely depending on the condition being treated and may range from 5 mg to over 60 mg per day. Your doctor may adjust your dose gradually, especially if you have been using it for a long time. Follow your doctor’s directions exactly and do not stop taking Prednisone suddenly, as this may lead to withdrawal symptoms or adrenal insufficiency. If you are using a dose-tapering schedule, follow it carefully.
Before taking Prednisone, inform your doctor if you have any current infections, liver or kidney disease, heart problems, diabetes, high blood pressure, osteoporosis, eye conditions like glaucoma or cataracts, or a history of mental health issues. This medication may lower your body’s ability to fight infections. Avoid contact with people who are sick or recently vaccinated with live vaccines. Long-term use may lead to bone loss, vision changes, or hormone imbalance. Regular checkups and lab tests may be required to monitor your health during treatment.
Prednisone should not be used in patients with systemic fungal infections or known hypersensitivity to the drug or other corticosteroids. It is also contraindicated in individuals receiving live or attenuated live vaccines while on immunosuppressive doses of Prednisone. Use during pregnancy or breastfeeding must be carefully evaluated by a healthcare provider. Prednisone should be prescribed only when the benefits outweigh the risks in such cases.
Common side effects of Prednisone include increased appetite, weight gain, insomnia, mood changes, indigestion, and acne. Long-term use may result in more serious issues such as high blood pressure, muscle weakness, osteoporosis, slow wound healing, glaucoma, and Cushing's syndrome. Rare but serious side effects include vision problems, severe allergic reactions, or mental changes such as depression or psychosis. Contact your doctor if you notice unusual symptoms or if common side effects become bothersome or persistent.
Prednisone can interact with many drugs, including NSAIDs (like ibuprofen), blood thinners (warfarin), diuretics, vaccines, antifungal medications, and some antibiotics. These interactions may increase the risk of side effects such as bleeding, infection, or reduced effectiveness of either medication. Always provide your healthcare provider with a full list of your current medications, including over-the-counter drugs and supplements, to avoid potentially harmful interactions.
If you miss a dose of Prednisone, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and resume your regular dosing schedule. Do not take a double dose to make up for the missed one. Missing multiple doses may affect your treatment, especially if you are on a tapering schedule. Contact your healthcare provider for advice if needed.
Overdose symptoms may include severe swelling, high blood pressure, vision changes, extreme fatigue, or sudden mood swings. Long-term excessive use may lead to serious hormonal imbalances or Cushing’s syndrome. If overdose is suspected, seek immediate medical attention. Emergency treatment focuses on stabilizing vital signs and preventing complications related to corticosteroid excess.
Store Prednisone tablets at room temperature between 15°C and 30°C (59°F and 86°F), in a dry place away from moisture, heat, and light. Do not store in the bathroom. Keep the bottle tightly closed and out of reach of children and pets. Dispose of expired or unused medication according to your pharmacist’s or local authority’s instructions.
Prednisone is legally available through The Urological Institute of Northeastern New York, a certified and licensed online pharmacy offering safe and approved access to corticosteroid treatment options for patients across the United States.